插入了Velocigene cassette ZEN-Ub1导致了染色体5(Genome Build37)137,511,559-137,519,109位点之间75,51bp的缺失,随后通过Cre介导的剔除操作移除了新霉素选择 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count