来自项目Bmp2k-5786J-8977的这个等位基因是在Jackson实验室通过注入Cas9 nickase RNA和左向引物GGCGAACACCCGGACCCCCA,以及右向引物CGGCCGCTACCAGGTCACCC产生的,导致了5号染色体正链9,699,7992bp位置起始的163bp缺失,延伸到9,699,8155bp,预测会引发一个导致早期截断的frameshift变异。(J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
基因内删除
不确定
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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