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中文
通过将exon 2替换为由loxP位点介导的neo选择标记，产生了突变小鼠。RT-PCR确认了表达的转录本中exon 2缺失。表达的蛋白质在催化部位缺失了与Fe2+结合的2个必需氨基酸，导致酶活性完全丧失。(来源：J:213191)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
