ENU induced a T to G transversion at base pair 4,339,552 (v38) on chromosome 18, or base pair 13,930 in the GenBank genomic region NC_000084. The mutation corresponds to residue 942 in the NM_007746 mRNA sequence in exon 5 of 8 total exons. The mutation results in a leucine (L) to arginine (R) substitution at amino acid residue 273. (J:212899)