这个构建设计是为了从5'到3'插入一个FRT位点、鸡β-actin启动子(CAG)、一个由loxP标记的终止子、人类IDH2带有R140Q突变、一个PGK的Hygro-polyA序列,以及另一个FRT位点到小鼠胶原A1基因座。(来源:J:209629)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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