设计了一个靶向构建,用于替换基因exon1和内含子1的部分,通过插入优化的Cre重组酶基因(iCre)、内源性核糖体进入信号(IRES)、增强绿色荧光蛋白(EGFP)、poly(A)序列,以及Frt标签的诺卡霉素/卡那霉素抗性(neo/kan)载体。(来源:J:211105)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
--
27

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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