一个nLacZ基因在编码前13个氨基酸的DNA序列中发生了内切并插入,导致小段缺失,进而打断了基因并使得在内源性启动子调控下nLacZ的表达。下游插入了TK-诺卡因抗性基因座。原位杂交分析显示Myf5和Myf6的表达缺失。(引用文献:J:16491, J:33706)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count