一个nLacZ基因在编码前13个氨基酸的DNA序列中发生了内切并插入,导致小段缺失,进而打断了基因并使得在内源性启动子调控下nLacZ的表达。下游插入了TK-诺卡因抗性基因座。原位杂交分析显示Myf5和Myf6的表达缺失。(引用文献:J:16491, J:33706)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
2
32

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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