Exon 2被替换成一个带有floxed Neo抗性标记、终止子、LoxP位点、去除了N端编码序列的人源ETV1cDNA(包括内含子和GFP以及polyA序列),通过Cre介导的重组,移除了选择和终止子元件,从而实现了融合产物和报告基因的表达。(来源:J:212219)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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