这个靶向构建在exon 2上游插入了FRT位点、拼接接受器、IRE斯序列、β-geo插入片段、poly(A)序列、另一个FRT位点和loxP标记。随后,通过Flp介导的重组,移除了含FRT标记的β-geo片段,使得exon 2成为可翻转的。来源:(J:211898)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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