这个靶向构建插入了a CAG启动子、loxP位点、诺卡因抗性/STOP序列、loxM位点,以及一个包含loxP和loxM位点的倒置序列,序列中包含VP16激活器、IRES、Venus报告基因和polyadenylation序列。要实现这个倒置序列的表达,需要Cre介导的重组。(来源:J:210076)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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