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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(CAG-Ubqln1)2Hmw
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基础信息
表型特征
文献报道
这个转基因表达的是全长的mouse Ubqln1 cDNA,由CMV增强子/鸡β-actin启动子驱动。免疫印迹分析显示,大脑、心脏、肝脏和骨骼肌中存在显著的过表达,而在其他组织中则以较低水平体现。(来源:J:206930)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5576803
C57BL/6 x SJL
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插入
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1
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3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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