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经卵鼠胚胎移植的受精卵中，加入了来源于HyHEL10浆细胞瘤细胞系的重组重链V(D)J区段（包括重链可变区和κ轻链VJ区段）和κ轻链的VJ区段。这些重链的变体区连接到Ighd恒定区和Igha亚型的膜端外显子，而轻链的变体区则与Igk恒定区及Igka亚型3'端的DNA相连。每个构建体都在V区段序列上游的启动子驱动下表达。来源：(J:139863)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
