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中文
Exon 2被替换为一个，其中的核苷酸替换(AAG替换为TCG，AAA替换为TCT)导致第24和25位氨基酸由丝氨酸(Ser)变为赖氨酸(Kys，即K24S和K25S)。在Exon 4引入了一个早停密码子，阻止了最后30个氨基酸的翻译。预测产物将无法与硫酸基团结合，但不影响CXCR4依赖的细胞信号。通过Cre介导的重组，去除了位于Exon 3下游的含Neo抗性基因的克隆。(来源：J:209558)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
