在上游内含子中插入了两个LoxP位点,它们位于5-10号外显子的两侧,以及一个Frt介导的诺卡因选择标记。通过Flp介导的重组移除了诺卡因,而Cre介导的重组在生殖细胞中删除了5-10号外显子。(来源:J:208092)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S/SvEv)F1
Targeted
插入,基因内删除
--
1
10
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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