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中文
在第12外显子上游插入了loxP位点。在第12外显子下游插入了FRT-和loxP标记的诺卡因抗性元件。通过Flp介导的重组移除了选择性元件，使得第12外显子成为可删除区域。随后，Cre介导的重组剔除了第12外显子，导致了C端的过早截断。 Western blot分析证实了骨髓衍生的巨噬细胞中该截短蛋白的低表达水平。(来源：J:207113)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
