Mpdz^em1(IMPC)J

This allele from project Mpdz-5657J-A was generated at The Jackson Laboratory by injecting Cas9 nickase RNA and guide sequences GCAGGATGCTAATGGCCTGC and TGCCAGAGGATCTTTGCCGC, which resulted in a 136 bp deletion of TGTGATTGCCAGAGGATCTTTGCCGCCGGTCTCCAGCCCACGGATTTCCCGCTCTCCATCAGCAGCCAGCACCATTTCAGCCCACTCGAATCCAGTGAGTAGCAGAGGCCCAGGATCGGAAGGTGCCACCTCTGGT and a 29 bp insertion of AATAACCCTAAAAGGTTAAAATATTAAAC in exon 6 beginning at Chromosome 4 negative strand position 81383820 bp (GRCm38) and is predicted to cause a frameshift mutation with early truncation. (J:188991)