这个转基因包含了牛甲状腺球蛋白(TG)的启动子,以及人TPR和人NTRK1的融合产物,这是人类乳头状甲状腺癌中观察到的。转基因表达和甲状腺特异性表达通过RNA酶保护分析进行了验证。Line 5215是建立的三线之一。(来源:J:67120)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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