在J:208420中,描述的是一项基因编辑技术。他们插入了一个带有lacZ报告基因的FRT-终止子 cassette,接着是loxP-标记的exon 5和rox-标记的PGK-hygromycin筛选 cassette。通过Dre重组,PGK-hygromycin的选择 cassette被剔除了。随后,Flp介导的重组活动移除了终止子 cassette,使得exon 5成为可调节的,也就是floxed。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部