设计了一个靶向载体,它在exon 4周围插入了loxP位点,同时包含了一个由frt序列引导的诺卡因抗性(neo)基因座。通过FLP介导的重组,去除了frt引导的neo基因座。(来源:J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6Brd-Tyrc-Brd x 129S6/SvEvTac)F1
Targeted
插入
--
1
--
49

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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