在第四外显子上游插入了loxP位点,下游则插入了floxed的hygromycin抗性基因座。通过Cre介导的重组,去除了4到6号外显子以及选择性座。 Western blot结果显示肾上腺和白色脂肪组织(包括肾上腺周和生殖腺)中没有蛋白表达。(来源:J:208505)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部