(IMAGE clone BAC RP24-186D18被修改,以表达人源化COP4(也称为通道光受体-2或ChR2),它带有H134R(第134位 Histidine到Arginine)的突变,连接到EYFP(ChR2(H134R)EFYP),由小鼠Pcp2基因调控元件驱动。这种高表达在大脑皮层的 Purkinje细胞和视网膜的 rod bipolar细胞中可见。(来源:201128)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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