在基因的第4内含子和5-7外显子间插入了一个FRT引导的诺姆卡斯汀片段,同时5-7号外显子被loxP位点包裹。在胚胎干细胞中短暂表达FLP重组酶后,去除了诺姆卡斯汀片段,留下了含loxP标记的5-7号外显子。(来源:J:217860)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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