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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Med23
tm1.1Pkb
Alias:
Med23
flox
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基础信息
表型特征
文献报道
在基因的第4内含子和5-7外显子间插入了一个FRT引导的诺姆卡斯汀片段,同时5-7号外显子被loxP位点包裹。在胚胎干细胞中短暂表达FLP重组酶后,去除了诺姆卡斯汀片段,留下了含loxP标记的5-7号外显子。(来源:J:217860)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5568337
129S6/SvEvTac
Targeted
插入
--
1
3
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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