从BAC克隆144L21中提取了一个1.1kb的DNA片段,包含第39和40外显子,然后通过PCR引入了E1841K的突变到第39外显子。在第39外显子上游插入了一个可删除的诺卡因选择标记,但之后通过Cre表达被去除了。(来源:J:175367)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入
--
1
9
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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