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中文
这种人类FGFR1，其酪氨酸激酶域的自动抑制环中lysine656被替换为 glutamic酸，由前列腺特异性大鼠probasin驱动序例调控。这种突变改变了酪氨酸激酶域的自动抑制环构象，使其在没有FGFR复合物外部激活的情况下暴露了激酶的催化位点，从而产生了持续激活的FGFR1。建立了三线。当未指明或线条混杂时，使用pound符号(#)表示。参考文献：(J:87519)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
