第14外显子被替换为一个插入了急性髓系白血病患者ITD(AGGACTGATTTCAGCGAA)的第14外显子。下游位置放置了一个敲除neo cassette,由Cre介导的重组移除了neo cassette。(来源:J:133528)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion, Single point
--
1
11
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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