设计了一个靶向载体,用于将内源性LIM同源盒蛋白8(Lhx8)基因的终止密码子替换为(从5'至3'):一段病毒2A多肽(以促进核糖体跳过),Cre重组酶,另一段2A多肽,青蓝荧光蛋白(GFP)的cerulean变异型,以及牛的poly(A)序列。(来源:J:195615)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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