这个等位基因包含一个FRT引导的诺姆抗性元件,以及这个元件两侧各有两个loxP位点,它们环绕着exon 6。通过Cre介导的重组,去除了选择性元件和exon 6。 Western blot结果显示,小鼠胚胎成纤维细胞中没有检测到蛋白表达。(来源:J:205601)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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