这个构建包含了TRE3G(第三代tet响应驱动子),EmGFP区域(Mirlet7a与修改过的mir155尾部环的融合),一个SV40polyadenylation信号,13kb的mouse Vil1启动子,以及rtTA-M2序列。Mirlet7a/mir155融合的shRNA不被LIN28A或LIN28B识别。(来源:J:202923)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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