Log In|Sign Up
中文
这个转基因表达的是携带瑞典K670N和M671L(Swe)以及奥地利T714I(Aut)家族阿尔茨海默病突变的人类APP695，它在Thy1.2启动子的调控下在神经元中表达。免疫印迹结果显示，转基因人类APP蛋白的表达大约是野生型小鼠App的1.4倍。(来源：J:204270)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
