在第8个外显子上游插入了一个loxP位点。下游的9号外显子位置插入了一个FRT引导的诺卡因抗性基因座,带有内含子(IRES)和一个5'的loxP位点作为剪接供体。通过Flp介导的重组,选择性基因座被去除,剩下的8号和9号外显子被标记为可删除的。(来源:J:204996)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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