Cre介导的重组移除了转录终止子,使得含有在克氏细胞增生症患者中常见(lysine到glutamate替换,K267E)的修改编码区域得以表达。(来源:J:207367)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6(Cg)-Tyrc-2J/J
Targeted
Insertion, Nucleotide substitutions
--
1
6
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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