在内皮1中插入了一个带有floxed停止 cassette的cDNA片段,该片段编码小鼠Notch3的细胞内域(1668到2318氨基酸),后面跟着IRES序列和YFP序列。Notch3片段作为持续激活的受体起作用。(来源:J:201985)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
Targeted
插入
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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