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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Hprt1
tm3(Ar-luc)Geno
Alias:
ARE-Luc
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基础信息
表型特征
文献报道
将靶向构建插入到定位点,激活了内源性Ar启动子(SC1.2-ARE),驱动并rogen介导的荧光素酶活性(ARE-Luc),并重建了Hprt基因。(来源:J:205903)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5555881
129P2/OlaHsd
Targeted
插入
--
1
2
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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