插入了Velocigene cassette ZEN-Ub1导致了染色体11(基因组Build37)上9,443,3544-9,446,3081位置之间29,538个碱基的缺失,随后通过Cre介导的剔除操作移除了新霉素选择 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count