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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Slc6a3-icre)9190Gsc
Alias:
DATCre
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基础信息
表型特征
文献报道
改进后的密码子cre阅读框被插入到Slc6a3的起始翻译位点,生成了一个能驱动cre在大脑中表达的转基因。产生了9075(两个拷贝转基因)、9190(三个拷贝)和9140(五个拷贝)这些转基因品系。(来源:J:114551)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
5554573
FVB/N
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插入
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2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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