Tg(Ckm-Pnpla2)164Eek

A modified creatine kinase muscle specific promoter drives expression of the full length Pnpla2 cDNA including 418 bp of 3' sequence containing the polyA signal. The modified promoter contains the murine Ckm promoter and enhancer E1, untranslated exon 1, intron 1 including enhancer E2, the first 16 bp of exon 2 and an SV40 polyA signal. Several lines were generated including: 1 and 164. This is a representative record for both lines. (J:207007)