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中文
带有双向CMV启动子的四环素应答元件驱动对人类MAPT(TauRD, 244-372aa)中，携带有17号染色体Lys280缺失(ΔK280)和两个六肽位点的脯氨酸突变(如I277P和I308P)的四重复区域的诱导性表达。Lys280的缺失促进聚集，而脯氨酸突变抑制MAPT( Tau)的聚集。(来源：J:131379)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
