Myh10^b2b2437Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a T to C substitution at coding nucleotide 1054 in exon 10 of the cDNA (c.1054T>C, NM_175260). This changes the serine residue to proline at position 352 of the encoded protein (p.S352P). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Myh10b2b2437Clo, and may be present in stocks carrying this mutation.