在19号外显子上游插入了loxP位点,下游则插入了带有Neo抗性标记的克隆Neo cassette。通过Cre介导的重组,19号至25号共五个编码区域和抗性元件都被去除。RT-PCR结果显示衍生的巨噬细胞中没有转录表达的信号。(来源:J:202853)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部