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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Myh9
tm1.1Dash
Alias:
Myh9
R702C
R702C+
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基础信息
表型特征
文献报道
在exon 16中的核苷酸替换导致了第702位的氨基酸由 cysteine 替换为 arginine(R702C)。通过Cre介导的重组,去除了位于exon 15上游的含荧光素的诺卡因抗性基因座。(来源:J:204923)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
5551833
129S2/SvPas
Targeted
Insertion, Nucleotide substitutions
--
1
9
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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