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中文
融合蛋白，由Cre重组酶和人类雌激素受体(ERT2)突变的配体结合域组成，被插入到第1内含子。雌激素受体包含G400V、M543A和L544A三种突变，这些突变增强了对Tamoxifen的敏感性。口服Tamoxifen后，重组效率在目标等位基因和组织间可从50%至几乎100%不等，脑部的重组率最低。(来源：J:126518)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
