J1-4区域被替换成J558 H10家族驱动子、H10分段 leader序列、重组的人类重链抗体4E10(一种自身/多反应性,针对gp41的BnAb)以及一个floxed Neo抗性基因座。随后,Cre介导的重组移除了Neo基因座。(来源:J:205708)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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