Exon 2和3被替换为一个全长的cDNA,其中包含导致第350位氨基酸由苯丙氨酸替换为 cysteine( F350C) 的核苷酸变异,并附有一个绿色荧光蛋白(GFP)和一个floxed Neo抗性基因座。随后,通过Flp介导的重组去除了选择性 cassette。(来源:J:205754)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Nucleotide substitutions
--
1
6
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部