通过同源重组技术,在Foxl2基因的终止密码子后259bp位置插入了IRES-cre/ERT2-Frt-neo-Frt序列。这些转基因小鼠杂交至C57BL/6背景的鼠,F1代再与flp表达的鼠交配以去除neo标记。(来源:J:206011)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
插入
--
1
3
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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