将转基因载体构建时,将小鼠Mmp20的cDNA插入到了位于mouse amelogenin启动子(4639bp)和包含amelogenin 3'非编码区(1127bp,包括amelogenin polyadenylation sites)的序列之间。Founder 42在未表达内源性Mmp20基因的小鼠中,产生了Mmp20的低水平表达。(来源:J:206207)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count