将转基因载体构建时,将小鼠Mmp20的cDNA插入到了位于mouse amelogenin启动子(4639bp)和包含amelogenin 3'非编码区(1127bp,包括amelogenin polyadenylation sites)的序列之间。Founder 42在未表达内源性Mmp20基因的小鼠中,产生了Mmp20的低水平表达。(来源:J:206207)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
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插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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