在exon 2上游插入了FRT-和loxP引导的诺卡因抗性基因座,exon 2下游也插入了loxP位点。通过Flp介导的重组移除了诺卡因抗性基因座,随后Cre介导的重组去除了exon 2。反转录PCR证实了骨组织中没有转录表达。(来源:J:201631)
Basic Information
(C57BL/6NTac x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count