插入了Velocigene cassette ZEN-Ub1导致了16号染色体(基因组Build37)上28622bp的缺失,具体位置在23,491,999-23,520,620。随后通过Cre介导的剔除,删除了含诺美西林选择标记的 cassette。(来源:J:136110, J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count