将一段852bp的mouse Cdx2基因内含神经特异性增强子的1号内含子片段,与cre重组酶表达盒连接。cre盒包含Hsp68的最小启动子、cre重组酶编码序列和SV40的polyadenylation序列。这个构建物被注入到(C57BL/6 x C3H)的卵母细胞中。获得了13个F0代,其中8个检测出cre活性。一只名为R337的雄性个体与野生型B6雌性杂交。(来源:J:204467)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x C3H
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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