带有3' loxP位点的诺美西林抗性基因座替换掉了第四外显子(编码第三外显子的区域)。 Western blot结果显示肝脏、肺和鼻腔嗅觉黏膜中没有检测到蛋白表达。(来源:J:204727)
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A neomycin resistance cassette with a 3' loxP site replaced exon 4 (coding exon 3). Western blot analysis confirmed the absence of protein expression in the liver, lung and nasal olfactory mucosa. (J:204727)