Log In|Sign Up
中文
L1L2_Bact_P cassette被插入到染色体2的38,632,589位置，位于关键exon7的上游(基于GRCm39构建)。该 cassette包含FRT位点、lacZ序列和一个loxP位点。FRT位点后面跟着由人类β-actin启动子驱动的诺卡因抗性基因、SV40polyA，然后是第二个FRT位点和第二个loxP位点。第三个loxP位点插入在目标exon7下游的38,633,441位置。因此，关键exon7被loxP位点所夹峙。通过Flp介导的重组移除了报告和选择元件，而Cre介导的重组则去除了exon7(来源：J:204241)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
